NO EVIDENCE OF GENETIC ASSOCIATION BETWEEN DRD3 VARIANTS AND TARDIVE DYSKINESIA IN KOREAN SCHIZOPHRENIC PATIENTS
β Scribed by Jimmy Lee; Seung-Hyun Kim; Leen Kim
- Book ID
- 119557415
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 77 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0920-9964
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Neuroleptic induced akathisia is a common and distressful extrapyramidal side effect of antipsychotic treatment. A significant proportion of the variability of its development has been left unexplained and has to be attributed to individual susceptibility. Since hereditary factors have been discusse
## Abstract ## Objective Tardive dyskinesia (TD) is a longβterm adverse effect of antipsychotic. We evaluated candidate functional polymorphism of the G protein __Ξ²__3 subunit (GNB3) gene for association with drugβinduced TD in the Korean schizophrenic patients. ## Methods We investigated whethe