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No association of three GRIN2B polymorphisms with lithium response in bipolar patients

✍ Scribed by Szczepankiewicz, Aleksandra; Skibiñska, Maria; Suwalska, Aleksandra; Hauser, Joanna; Rybakowski, Janusz K.

Book ID
122183463
Publisher
Elsevier
Year
2009
Tongue
English
Weight
116 KB
Volume
61
Category
Article
ISSN
1734-1140

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## Abstract __FYN__ belongs to the protein kinase family that phosphorylates NMDA receptor subunits, participating in the regulation of ion transmission and BDNF/TrkB signal transduction pathway. Lithium inhibits glutamatergic transmission via NMDA receptors, exerting neuroprotective effect against