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Association study of the glycogen synthase kinase-3β gene polymorphism with prophylactic lithium response in bipolar patients

✍ Scribed by Szczepankiewicz, Aleksandra; Rybakowski, Janusz K.; Suwalska, Aleksandra; Skibinska, Maria; Leszczynska-Rodziewicz, Anna; Dmitrzak-Weglarz, Monika; Czerski, Piotr M.; Hauser, Joanna


Book ID
121273715
Publisher
Informa plc
Year
2006
Tongue
English
Weight
72 KB
Volume
7
Category
Article
ISSN
1562-2975

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## Abstract __FYN__ belongs to the protein kinase family that phosphorylates NMDA receptor subunits, participating in the regulation of ion transmission and BDNF/TrkB signal transduction pathway. Lithium inhibits glutamatergic transmission via NMDA receptors, exerting neuroprotective effect against