Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in the synthesis of 5-hydroxytryptamine (5-HT). An association study in bipolar affective disorder I or unipolar major affective disorder was performed by using a Bfa I restriction site polymorphism within intron 7 of the tryptophan hydroxylas
β¦ LIBER β¦
No Association of theYWHAEGene with Schizophrenia, Major Depressive Disorder or Bipolar Disorder in the Han Chinese Population
β Scribed by Jie Liu; Guoquan Zhou; Weidong Ji; Junyan Li; Tao Li; Ti Wang; You Li; Zhen Zeng; Zhiwei Hu; Linqing Zheng; Jue Ji; Yang Wang; Zhiyun Wei; Guoyin Feng; Lin He; Yongyong Shi
- Publisher
- Springer US
- Year
- 2010
- Tongue
- English
- Weight
- 189 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0001-8244
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A recent Japanese study on the angiotensin I converting enzyme gene (ACE) insertion/ deletion polymorphism reported that both the D allele (P < 0.02) and the DD genotype (P < 0.002) were significantly more frequent in affective disorder cases than in controls [Arinami et al., 1996: Biol Psychiatry 4