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No Association of the Structural Dopamine D2 Receptor (DRD2) Variant 311Cys with Alcoholism

✍ Scribed by Ulrich Finckh; Ole von Widdern; Mario Giraldo-Velasquez; Jan Podschus; Peter Dufeu; Thomas Sander; Helmut Harms; Lutz G. Schmidt; Hans Rommelspacher; Arndt Rolfs

Book ID
114749773
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
497 KB
Volume
20
Category
Article
ISSN
0145-6008

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No evidence for association of dopamine
No evidence for association of dopamine D2 receptor variant (Ser 311/Cys311) with major psychosis
✍ Sasaki, Tsukasa; Macciardi, Fabio M.; Badri, Farideh; Verga, Massimiliano; Meltz πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 331 KB πŸ‘ 1 views

We investigated a variant of the dopamine D2 receptor gene (Ser311/Cys311 substitution) in Caucasian patients with schizophrenia (n = 273), delusional disorder (n = 621, bipolar I affective disorder (n = 63), and controls (n = 255). No evidence for association between the receptor variant and any of

No association of dopamine D2 receptor m
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✍ Chen, Chia-Hsiang; Chien, Shih-Hsiang; Hwu, Hai-Gwo πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 305 KB πŸ‘ 1 views

A serine-to-cysteine mutation of dopamine D2 receptor at codon 311 (Cys311) was found to have higher frequency in schizophrenic patients than in normal controls in Japanese by Arinami et al. 11994: Lancet 343: 703-7041. The Cys311 allele was found to be associated with patients with younger ageof-on

Lack of association between dopamine D2
Lack of association between dopamine D2 receptor gene Cys311 variant and schizophrenia
✍ Tanaka, Toshihisa; Igarashi, Shuichi; Onodera, Osamu; Tanaka, Hajime; Fukushima, πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 12 KB πŸ‘ 2 views

reported identifying one missense nucleotide mutation from C to G resulting in a substitution of serine with cysteine at codon 311 in the third intracellular loop of the dopamine D2 receptor in schizophrenics. Arinami et al. 119941 reported finding a positive association between the Cys311 variant a