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No association of germline alteration of MSR1 with prostate cancer risk

โœ Scribed by Wang, Liang; McDonnell, Shannon K; Cunningham, Julie M; Hebbring, Scott; Jacobsen, Steven J; Cerhan, James R; Slager, Susan L; Blute, Michael L; Schaid, Daniel J; Thibodeau, Stephen N


Book ID
109918777
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
101 KB
Volume
35
Category
Article
ISSN
1061-4036

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Germline mutations of the MSR1 gene in p
โœ Christiane Maier; Zorica Vesovic; Natascha Bachmann; Kathleen Herkommer; Anja K. ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 214 KB ๐Ÿ‘ 1 views

The MSR1 gene at 8p22 has been suggested as a candidate gene for hereditary prostate cancer because germline variants have been found to be associated with the disease. Aside from a single nonsense mutation (R293X) that was found repeatedly at low frequencies in several samples, little evidence has