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No association of DPP6 with amyotrophic lateral sclerosis in an Italian population

✍ Scribed by Isabella Fogh; Sandra D’Alfonso; Cinzia Gellera; Antonia Ratti; Cristina Cereda; Silvana Penco; Lucia Corrado; Gianni Sorarù; Barbara Castellotti; Cinzia Tiloca; Stella Gagliardi; Lorena Cozzi; Michelle K. Lupton; Nicola Ticozzi; Letizia Mazzini; Chris E. Shaw; Ammar Al-Chalabi; John Powell; Vincenzo Silani


Book ID
116781522
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
106 KB
Volume
32
Category
Article
ISSN
0197-4580

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High frequency of TARDBP gene mutations
✍ Lucia Corrado; A. Ratti; C. Gellera; E. Buratti; B. Castellotti; Y. Carlomagno; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 183 KB

Recent studies identified rare missense mutations in amyotrophic lateral sclerosis (ALS) patients in the TARDBP gene encoding TAR DNA binding protein (TDP)-43, the major protein of the ubiquitinated inclusions (UBIs) found in affected motor neurons (MNs). The aim of this study was to further define