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Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis

✍ Scribed by van Es, Michael A; van Vught, Paul WJ; Blauw, Hylke M; Franke, Lude; Saris, Christiaan GJ; Van Den Bosch, Ludo; de Jong, Sonja W; de Jong, Vianney; Baas, Frank; van't Slot, Ruben


Book ID
109914276
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
222 KB
Volume
40
Category
Article
ISSN
1061-4036

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## Abstract Amyotrophic lateral sclerosis‐parkinsonism dementia complex (ALS/PDC) is a distinct neurodegenerative disorder characterized by ALS pathology with neurofibrillary tangles (NFTs) in the spinal cord and brain. Recent clinical studies have revealed a high incidence and a high familial occu