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No association between the 308 polymorphism in the tumour necrosis factor alpha (TNFalpha) promoter region and polycystic ovaries

✍ Scribed by Milner, C.R.


Book ID
127323473
Publisher
Oxford University Press
Year
1999
Tongue
English
Weight
124 KB
Volume
5
Category
Article
ISSN
1360-9947

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The striking evidence of almost 100% association of narcolepsy with human leukocyte antigens (HLA) DR2(DR15) antigen is an important clue to elucidate the molecular basis of this sleep disorder. The gene for tumor necrosis factor ␣ (TNF ␣) is located in the HLA class II gene cluster. Recent studies