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No association between high temperature requirement 1 (HTRA1) gene polymorphisms and Alzheimer's disease

✍ Scribed by Mari Turunen; Saila Vepsäläinen; Petra Mäkinen; Seppo Helisalmi; Annakaisa Haapasalo; Hilkka Soininen; Mikko Hiltunen


Book ID
116781539
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
120 KB
Volume
32
Category
Article
ISSN
0197-4580

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To examine the possible involvement of the alpha-1-antichymotrypsin gene (ACT) polymorphism in the manifestation of Alzheimer's disease (AD), we analyzed genotypes of the ACT and apolipoprotein E gene (APOE) among 110 Korean patients with probable AD and 209 nondemented controls. No significant diff