synthesized in the liver and is regulated by a gene located Genetic hemochromatosis and a 1 -antitrypsin (AAT) on chromosome 14 for which several alleles have been dedeficiency are frequent in white populations. Conflictscribed. The most common allele, PiM, is associated with an ing data on the asso
No association between genetic hemochromatosis and alpha1-antitrypsin deficienc
β Scribed by S Fargion; F Bissoli; AL Fracanzani; E Suigo; C Sergi; E Taioli; R Ceriani; V Dimasi; A Piperno; M Sampietro; G Fiorelli
- Book ID
- 118686459
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 167 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0270-9139
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Primary hemochromatosis is a genetically determined autosomal recessive disorder characterized by the excessive accumulation of body iron, most of which is deposited in the parenchymal cells of various organs. a,-Antitrypsin deficiency is characterized among others by defective secretion of a,-anti
Mieli-Vergani G. Value of urinary copper excretion after penicillamine challenge in the diagnosis of Wilson's disease. HEPATOLOGY
To examine the possible involvement of the alpha-1-antichymotrypsin gene (ACT) polymorphism in the manifestation of Alzheimer's disease (AD), we analyzed genotypes of the ACT and apolipoprotein E gene (APOE) among 110 Korean patients with probable AD and 209 nondemented controls. No significant diff