N,N′ -Dioxide-Magnesium Ditriflate Complex-Catalyzed Asymmetric α-Hydroxylation of β-Keto Esters and β-Keto Amides
✍ Scribed by Yin, Chengkai; Cao, Weidi; Lin, Lili; Liu, Xiaohua; Feng, Xiaoming
- Book ID
- 120421760
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 395 KB
- Volume
- 355
- Category
- Article
- ISSN
- 1615-4150
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## Abstract The asymmetric hydroxylation of indan‐1‐one‐2‐carboxylates using phenyloxaziridine as oxidant is catalyzed by a novel axially chiral NHC—Pd catalyst (BINCAP).
A catalytic, enantioselective Michael addition of b-keto esters to a,b-unsaturated carbonyl compounds was achieved by using a chiral biquinoline N,N 0 -dioxide-scandium trifluoromethanesulfonate complex as a catalyst. The corresponding Michael adducts were obtained in high yields and with enantiosel
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