NMR studies on the structure of some cyclic and linear antagonists of luteinizing hormone-releasing hormone (LHRH)
✍ Scribed by REDDY, D.V. ;JAGANNADH, B. ;DUTTA, ANAND S. ;KUNWAR, A.C.
- Book ID
- 115099717
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Tongue
- English
- Weight
- 749 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0367-8377
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The synthesis of new photolabeling analogues of luteinizing hormone releasing hormone is described. Peptides were prepared by the solid-phasc method, and the photolabeling moiety was introduced as the 4'-nitrophenylalanine precursor. This amino acid, either of the L or u configuration, was placed at
## Abstract The structure of LH‐RH in DMSO solution was studied using 2D NMR experiments at 600 MHz. The ^13^C NMR spectrum was completely assigned by the combined use of ^1^H‐detected heteronuclear multiple‐quantum coherence and ^1^H‐detected multiple‐bond heteronuclear multiple‐quantum coherence.