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NMR spectral data for ester prodrugs of ganciclovir

✍ Scribed by Hongwu Gao; Ashim K. Mitra

Book ID: 101341285
Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 63 KB
Volume: 38
Category: Article
ISSN: 0749-1581
DOI: 10.1002/1097-458x(200008)38:8<696::aid-mrc655>3.0.co;2-6

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✦ Synopsis

A series of 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine mono-and diesters, 2a-i, 3a-d and 4a-d, were synthesized as potential prodrugs of ganciclovir and both 1 H NMR and 13 C NMR spectra were assigned to these esters based on spectral comparison with compounds of similar structure.

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