A series of 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine mono-and diesters, 2a-i, 3a-d and 4a-d, were synthesized as potential prodrugs of ganciclovir and both 1 H NMR and 13 C NMR spectra were assigned to these esters based on spectral comparison with compounds of similar structure.
NMR spectral data for acyclovir prodrugs
β Scribed by Hongwu Gao; Ashim K. Mitra
- Book ID
- 101252753
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 48 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0749-1581
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β¦ Synopsis
Both 1 H NMR and 13 C NMR spectra were assigned to a series of acyclovir ester and amide prodrugs. Assignments were based on spectral comparison with compounds of similar structure.
π SIMILAR VOLUMES
## Abstract Analyses of the ^1^H, ^13^C and ^19^F NMR spectra of 15 monoβ, diβ, triβ or tetrafluoroβsubstituted steroids were carried out by twoβdimensional ^1^Hο£Ώ^1^H and ^1^Hο£Ώ^13^C shift correlation experiments.
NMR spectroscopists are hindered by the lack of standardization for spectral data among the file formats for various NMR data processing tools. This lack of standardization is cumbersome as researchers must perform their own file conversion in order to switch between processing tools and also restri