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NMDA receptor hypofunction and animal models of schizophrenia

โœ Scribed by J.D. Jentsch; A.A. Grace; R.H. Roth


Book ID
119574571
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
316 KB
Volume
10
Category
Article
ISSN
0924-977X

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NMDA receptor hypofunction model of schi
โœ John W Olney; John W Newcomer; Nuri B Farber ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 195 KB

Several decades of research attempting to explain schizophrenia in terms of the dopamine hyperactivity hypothesis have produced disappointing results. A new hypothesis focusing on hypofunction of the NMDA glutamate transmitter system is emerging as a potentially more promising concept. In this artic