NMDA receptor hypofunction model of schi
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John W Olney; John W Newcomer; Nuri B Farber
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Article
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1999
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Elsevier Science
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English
โ 195 KB
Several decades of research attempting to explain schizophrenia in terms of the dopamine hyperactivity hypothesis have produced disappointing results. A new hypothesis focusing on hypofunction of the NMDA glutamate transmitter system is emerging as a potentially more promising concept. In this artic