NMDA Receptor and Schizophrenia: A Brief
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Coyle, J. T.
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Article
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2012
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Oxford University Press
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English
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Although glutamate was first hypothesized to be involved in the pathophysiology of schizophrenia in the 1980s, it was the demonstration that N-methyl-D-aspartate (NMDA) receptor antagonists, the dissociative anesthetics, could replicate the full range of psychotic, negative, cognitive, and physiolog