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[Nle4, D-Phe7]-α-MSH: A superpotent melanotropin with prolonged action on vertebrate chromatophores

✍ Scribed by Hadley, Mac E; Mieyr, John H; Martin, Brent E; De L. Castrucci, Ana M; Hruby, Victor J; Sawyer, Tomi K; Powers, Elaine A; Rao, K.Ranga


Book ID
121905610
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
707 KB
Volume
81
Category
Article
ISSN
0300-9629

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Toxicologic studies of a superpotent α-m
✍ Robert T. Dorr; Brenda V. Dawson; Fahad Al-Obeidi; Mac E. Hadley; Norman Levine; 📂 Article 📅 1988 🏛 Springer US 🌐 English ⚖ 611 KB

A toxicology study was performed in mice given a superpotent a melanocyte stimulating hormone (MSH) analog. This 13 amino acid derivative, [Nle 4, D-Phe7]c~-MSH or NDP-MSH, is a melanotropin which is very slowly biodegraded in vivo and is active at 1/1,000 the concentration of natural a-MSH. Mice we