Toxicologic studies of a superpotent α-m
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Robert T. Dorr; Brenda V. Dawson; Fahad Al-Obeidi; Mac E. Hadley; Norman Levine;
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Article
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1988
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Springer US
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English
⚖ 611 KB
A toxicology study was performed in mice given a superpotent a melanocyte stimulating hormone (MSH) analog. This 13 amino acid derivative, [Nle 4, D-Phe7]c~-MSH or NDP-MSH, is a melanotropin which is very slowly biodegraded in vivo and is active at 1/1,000 the concentration of natural a-MSH. Mice we