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NKG2D Blockade Prevents Autoimmune Diabetes in NOD Mice

✍ Scribed by Kouetsu Ogasawara; Jessica A Hamerman; Lauren R Ehrlich; Helene Bour-Jordan; Pere Santamaria; Jeffrey A Bluestone; Lewis L Lanier


Book ID
116570295
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
845 KB
Volume
20
Category
Article
ISSN
1074-7613

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1,25 dihydroxyvitamin D3, the active form of vitamin D, has immunomodulatory properties in vitro and in vivo. We report that treatment with 1,25 dihydroxyvitamin 03 (5 gg/kg on alternate days) prevents the development of clinical diabetes in NOD mice, an animal model of human autoimmune diabetes. Di

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