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Nitropyridyl Isocyanates.

โœ Scribed by Jarle Holt; Trygve Andreassen; Jan M. Bakke; Anne Fiksdahl


Publisher
John Wiley and Sons
Year
2005
Weight
20 KB
Volume
36
Category
Article
ISSN
0931-7597

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Nitropyridyl isocyanates
โœ Jarle Holt; Trygve Andreassen; Jan M. Bakke; Anne Fiksdahl ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 99 KB

We hereby report the first preparation of 3-nitro-4-pyridyl isocyanate 9 and 5-nitro-2-pyridyl isocyanate 18. They were formed by Curtius rearrangement of the corresponding acyl azides 8 and 17, prepared from methyl 3-nitro-4-pyridinecarboxylate 6 via the hydrazide 7 and 5-nitro-picolinic acid 16, r

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## Abstract magnified image The reactivity of 3โ€nitroโ€4โ€pyridyl isocyanate (**7**) and 5โ€nitropyridinโ€2โ€yl isocyanate (**9**) in 1,3โ€dipolar cycloaddition reactions with azides and pyridine __N__โ€oxides has been investigated. 1,3โ€Dipolar cycloaddition to trimethylsilylazide (TMSA) afforded the res

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