Nitrilium salts. New method for the synthesis of secondary amines
โ Scribed by Borch, Richard F.
- Book ID
- 120155593
- Publisher
- American Chemical Society
- Year
- 1969
- Tongue
- English
- Weight
- 441 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
secondary amlnes by palladium catalyst was explored (1). We now wish to report a novel method for synthesis of these amlnes from alcohols by utlllzlng versatile aminophosphomum reagent Ph3P+NR1R2 X-(.) (2). This method has certain advantages over the previous methods for
The clean and efficient cleavage of N-benzyl linked tertiary amines from a solid support (e.g. 4) by treatment with ct-chloroethyl chloroformate (ACE-CI) / methanol to yield secondary amines 7 is described. This allows the solid-phase synthetic transformation of the secondary amine 2 into 7. When th
A novel linker for the solid-phase synthesis of secondary amines based on an intramolecular cyclization was developed. The linker allows for a stepwise built-up of the secondary amines on the support. The feasibility was demonstrated in the parallel synthesis of a small set of different secondary am