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Nitric oxide synthases in the pathogenesis of cardiovascular disease

โœ Scribed by Hiroaki Shimokawa; Masato Tsutsui


Publisher
Springer
Year
2010
Tongue
English
Weight
301 KB
Volume
459
Category
Article
ISSN
0031-6768

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Nitric oxide (NO) is synthesized by at least three distinct isoforms of NO synthase (NOS). Their substrate and cofactor requirements are very similar. All three isoforms have some implications, physiological or pathophysiological, in the cardiovascular system. The endothelial NOS III is physiologica

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## Abstract Nitric oxide (NO) is a biologically active inorganic molecule produced when the semiessential amino acid lโ€arginine is converted to lโ€citrulline and NO via the enzyme nitric oxide synthase (NOS). NO is known to be involved in the regulation of many physiological processes, such as contr

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## Abstract Nitric oxide (NO) is a shortโ€living free molecule synthesized by three different isoforms of nitric oxide synthases (NOS)โ€”neuronal NOS, endothelial NOS, and inducible NOSโ€”associated with neuromuscular transmission, muscle contractility, mitochondrial respiration, and carbohydrate metabo