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Nitric Oxide Synthase Inhibitors Containing the Carboxamidine Group or Its Isosteres

✍ Scribed by S. Ya. Proskuryakov; A. G. Konoplyannikov; V. G. Skvortzov; A. A. Mandrugin; V. M. Fedoseev


Publisher
John Wiley and Sons
Year
2006
Weight
8 KB
Volume
37
Category
Article
ISSN
0931-7597

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## Abstract Some novel imidazolyl and pyrazolyl thiophene derivatives were synthesized. Different substituted __N__‐containing heterocycles were chosen with the aim of enhancing the activity or selectivity of the products towards inhibition of one of the three isoforms of nitric oxide synthase. One