Nitric oxide produced by inducible nitric oxide synthase is associated with mammary tumorigenesis in irradiated rats
β Scribed by Hiroshi Inano; Makoto Onoda
- Book ID
- 116789919
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 207 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1089-8603
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## Abstract Nitric oxide (NO), an important regulatory molecule for immune response and cytotoxicity, is endogenously generated from lβarginine by NO synthase (NOS). One mechanism for NOβinduced cytotoxicity is through its interaction with superoxide to produce peroxynitrite, which causes DNA damag