Nitric oxide (NO): an effector of apoptosis
✍ Scribed by Brüne, Bernhard; von Knethen, Andreas; Sandau, Katrin B
- Book ID
- 110015975
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 227 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1350-9047
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## Abstract Nitric oxide (NO) can regulate osteoblast activities. Our previous study showed that NO induced osteoblast apoptosis [Chen RM, Liu HC, Lin YL, Jean WC, Chen JS, Wang JH. Nitric oxide induces osteoblast apoptosis through the de novo synthesis of Bax protein. J Orthop Res 2002;20:295–302]
Amides were allowed to react with nitric oxide in aprotic and non-ethereal solvents to give the corresponding N-nittoso derivatives. The reaction was accelerated by addition of oxygen. The solvent effect revealed that the reaction did not proceed in the presence of protic media.