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Nitric oxide mediates cyclosporine-induced impairment of the blood–brain barrier in cocultures of mouse brain endothelial cells and rat astrocytes

✍ Scribed by Shinya Dohgu; Atsushi Yamauchi; Shinsuke Nakagawa; Fuyuko Takata; Mamiko Kai; Takashi Egawa; Mikihiko Naito; Takashi Tsuruo; Yasufumi Sawada; Masami Niwa; Yasufumi Kataoka


Book ID
113585116
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
553 KB
Volume
505
Category
Article
ISSN
0014-2999

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Nitric oxide-induced perturbations in a
✍ R.D. Hurst; I.B. Fritz 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 649 KB

The actions of an intracellular nitric oxide generator compound on the properties of a co-culture model of the blood-brain barrier are described. Addition of the iron-sulphur cluster nitrosyl Roussin's black salt (RBS, heptanitrosyl-tri-p3-thioxo- tetraferrate (1-1) resulted in a rapid and dose-depe