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Nitric oxide may contribute to nocturnal hemodynamic changes in cirrhotic patients

โœ Scribed by Joan Genesca; Rosa Segura; Antonio Gonzalez; Robert Catalan; Ramon Marti; Mireia Torregrosa; Ferran Cereto; Moises Martinez; Rafael Esteban; Jaime Guardia

Book ID
119388905
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
214 KB
Volume
95
Category
Article
ISSN
0002-9270

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Increased oxidative stress in cirrhotic rat livers: A potential mechanism contributing to reduced nitric oxide bioavailability
โœ Jorge Gracia-Sancho; Bร rbara Laviรฑa; Aina Rodrรญguez-Vilarrupla; Hรฉctor Garcรญa-Ca ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 612 KB

In cirrhotic livers, decreased nitric oxide (NO) bioavailability is a major factor increasing intrahepatic vascular tone. In several vascular disorders, an increase in superoxide (O 2 ุŠ ) has been shown to contribute to reduced NO bioavailability through its reaction with NO to form peroxynitrite. T