Increased oxidative stress in cirrhotic
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Jorge Gracia-Sancho; Bàrbara Laviña; Aina Rodríguez-Vilarrupla; Héctor García-Ca
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Article
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2007
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John Wiley and Sons
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English
⚖ 612 KB
In cirrhotic livers, decreased nitric oxide (NO) bioavailability is a major factor increasing intrahepatic vascular tone. In several vascular disorders, an increase in superoxide (O 2 ؊ ) has been shown to contribute to reduced NO bioavailability through its reaction with NO to form peroxynitrite. T