Activation of glia has been observed in various neurodegenerative diseases. Excessive production of nitric oxide (NO), as a consequence of increased inducible nitric oxide synthase (iNOS) in glia, contributes to the neurodegeneration. The enhancement of intracellular stresses such as oxidative stres
Nitric oxide-induced apoptosis in cultured rat astrocytes: Protection by edaravone, a radical scavenger
β Scribed by Toshiyuki Kawasaki; Tatsuya Kitao; Katsuhiro Nakagawa; Hiroko Fujisaki; Yoshimi Takegawa; Ken Koda; Yukio Ago; Akemichi Baba; Toshio Matsuda
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 524 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0894-1491
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Neuroinflammatory diseases are associated with increased production of matrix metalloproteinase-9 (MMP-9) and excessive generation of nitric oxide (NO). NO has been reported to have variable effects on MMP-9 gene expression and activation in various cell types. In the present study, we investigated
## Abstract The monocarboxylate transporter MCT4 is a protonβlinked carrier particularly important for lactate release from highly glycolytic cells. In the central nervous system, MCT4 is exclusively expressed by astrocytes. Surprisingly, MCT4 expression in primary cultures of mouse cortical astroc