Tumor necrosis factor-alpha is a principal mediator of the pathophysiological effects of endotoxemia and endotoxin shock. Tumor necrosis factor-a also contributes to the stimulation of nitric oxide synthesis by the induction of the enzyme nitric oxide synthase in a variety of tissues. Although the i
Nitric oxide in liver injury
โ Scribed by Mark G. Clemens
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 50 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
clusters. [3][4][5][6] Recently, the degree of hepatic inflammatory ac-Hepatitis C virus (HCV) causes acute and often also chronic tivity has been shown to be positively correlated to the exliver disease. Hepatocellular injury might result from both a pression of interferon-gamma (IFN-g) transcripts
Nitric oxide signalling during the past two decades has been one of the most rapidly growing areas in biology. This simple free radical gas can regulate an ever-growing list of biological processes. Here the regulation of NO synthesis in the liver is reviewed. The biogenesis of nitric oxide (NO) is
## **Acute and chronic ethanol treatment has been shown to increase the production of reactive oxygen species, lower cellular antioxidant levels, and enhance oxidative stress in many tissues, especially the liver. Ethanol-induced oxidative stress plays a major role in the mechanisms by which ethan