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Nitric Oxide Donor-Based Platinum Complexes as Potential Anticancer Agents

✍ Scribed by Jian Zhao; Prof. Dr. Shaohua Gou; Yanyan Sun; Dr. Runting Yin; Zhimei Wang


Book ID
115551606
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
735 KB
Volume
18
Category
Article
ISSN
0947-6539

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## Abstract Five licofelone ([2,2‐dimethyl‐6‐(4‐chlorophenyl)‐7‐phenyl‐2,3‐dihydro‐1__H__‐pyrrolizin‐5‐yl]acetic acid) nitric oxide donor conjugates were developed by a parallel synthesis approach. The biological screening revealed that compounds with a propyl (**6b**), butyl (**6c**), or octyl (**