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Nitric oxide and multiple sclerosis

✍ Scribed by Juan Manuel Encinas; Louis Manganas; Grigori Enikolopov


Book ID
107543442
Publisher
Springer
Year
2005
Tongue
English
Weight
328 KB
Volume
5
Category
Article
ISSN
1528-4042

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## Abstract Nitric oxide (NO) and peroxynitrite (ONOO^βˆ’^) are potential mediators of the injury and cytotoxicity occurring over time to oligodendrocytes in multiple sclerosis (MS) lesions. Our __in vitro__ results indicate that human adult CNS‐derived oligodendrocytes are relatively resistant to NO