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Nitric oxide and cyclic GMP regulate early events in agrin signaling in skeletal muscle cells

✍ Scribed by Earl W. Godfrey; Russell C. Schwarte

Book ID
113955998
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
737 KB
Volume
316
Category
Article
ISSN
0014-4827

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Ca2+ entry induced by N-methyl-D-aspartate (NMDA) in neurons and by noradrenaline (NA) in astrocytes is known to increase intracellular cyclic GMP (cGMP) levels through stimulation of the Ca2+-dependent nitric oxide synthase type I (NOS-I). The possibility that Ca2+ entry could also down-regulate in