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Up-regulation of Na+-dependent Mg2+ transport by nitric oxide and cyclic GMP pathway in renal epithelial cells

✍ Scribed by Akira Ikari; Kumiko Nakajima; Sayuri Taki; Yasunobu Suketa


Book ID
114015054
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
308 KB
Volume
451
Category
Article
ISSN
0014-2999

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Ca2+ entry induced by N-methyl-D-aspartate (NMDA) in neurons and by noradrenaline (NA) in astrocytes is known to increase intracellular cyclic GMP (cGMP) levels through stimulation of the Ca2+-dependent nitric oxide synthase type I (NOS-I). The possibility that Ca2+ entry could also down-regulate in