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Nitric Oxide Activates Metalloprotease Enzymes in Articular Cartilage

✍ Scribed by G.A.C. Murrell; D. Jang; R.J. Williams

Book ID
115575938
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
380 KB
Volume
206
Category
Article
ISSN
0006-291X

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## Abstract Articular chondrocytes are known to synthesize large amounts of nitric oxide in response to exposure to interleukin‐1, but the role of this radical in proteoglycan turnover remains controversial. In this study, we used two different inhibitors of nitric oxide synthase, N^G^‐methyl‐L‐arg