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Nitration inhibits fibrillation of human α-synuclein in vitro by formation of soluble oligomers

✍ Scribed by Ghiam Yamin; Vladimir N Uversky; Anthony L Fink

Book ID
117105342
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
241 KB
Volume
542
Category
Article
ISSN
0014-5793

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## Abstract Abnormal protein aggregation in the brain is linked to the pathogenesis of neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD). Recent studies revealed that the oligomeric form of aggregates is most likely the toxic species, and thus could be a go