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NIK is involved in constitutive activation of the alternative NF-κB pathway and proliferation of pancreatic cancer cells

✍ Scribed by Takashi Nishina; Noritaka Yamaguchi; Jin Gohda; Kentaro Semba; Jun-ichiro Inoue


Book ID
116298990
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
628 KB
Volume
388
Category
Article
ISSN
0006-291X

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## Abstract The transcription factor NF‐κB/Rel was found to be constitutively activated in human pancreatic cancer. RelA is present in the nucleus in primary human pancreatic cancer samples as well as in pancreatic cancer cell lines. NF‐κB/Rel–binding activity consists of NF‐κB1(p50) and RelA(p65).