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Nijmegen breakage syndrome linked to DNA-damage recognition

✍ Scribed by David Sharp


Book ID
117297592
Publisher
The Lancet
Year
1998
Tongue
English
Weight
117 KB
Volume
351
Category
Article
ISSN
0140-6736

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Nijmegen breakage syndrome: consequences
✍ Martin Digweed; AndrΓ© Reis; Karl Sperling πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 85 KB

The autosomal recessive genetic disorder, Nijmegen Breakage Syndrome, is characterised by an excessively high risk for the development of lymphatic tumours and an extreme sensitivity towards ionising radiation. The most likely explanation for these characteristics, a deficiency in the repair of DNA