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Nijmegen breakage syndrome and DNA double strand break repair by NBS1 complex

✍ Scribed by MATSUURA, S; KOBAYASHI, J; TAUCHI, H; KOMATSU, K

Book ID
119485316
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
969 KB
Volume
38
Category
Article
ISSN
0065-227X

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Nijmegen breakage syndrome: consequences
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✍ Martin Digweed; AndrΓ© Reis; Karl Sperling πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 85 KB

The autosomal recessive genetic disorder, Nijmegen Breakage Syndrome, is characterised by an excessively high risk for the development of lymphatic tumours and an extreme sensitivity towards ionising radiation. The most likely explanation for these characteristics, a deficiency in the repair of DNA