Nigrostriatal dysfunction in X-linked dystonia-parkinsonism (DYT3)
✍ Scribed by Björn Tackenberg; Aline Metz; Marcus Unger; Nicole Schimke; Sebastian Passow; Helmut Hoeffken; Georg F. Hoffmann; Ulrich Müller; Dagmar Nolte; Wolfgang H. Oertel; Karla Eggert; Jens Carsten Möller
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 149 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0885-3185
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## Abstract We report a patient with Lubag (X‐linked dystonia‐parkinsonism) who presented with severe respiratory stridor form adductor laryngeal breathing dystonia. Emergency tracheostomy was necessary, and subsequent laryngeal injection with botulinum toxin led to worsening aspiration. Botulinum
## Abstract “Lubag,” or Filipino X‐linked dystonia, typically presents with either pure dystonia (that inexorably becomes generalized) or combined dystonia–parkinsonism. We report on three cases of Lubag presenting with isolated parkinsonism without dystonia or late‐onset dystonia and a slower cour