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(-)-Nicotine Protects against Systemic Kainic Acid-Induced Excitotoxic Effects

โœ Scribed by Cesario V. Borlongan; Roland D. Shytle; Shajmil D. Ross; Toru Shimizu; Thomas B. Freeman; David W. Cahill; Paul R. Sanberg


Book ID
115606262
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
504 KB
Volume
136
Category
Article
ISSN
0014-4886

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## Abstract Metallothioneins I and II (MTI/II) are metalโ€binding proteins overexpressed in response to brain injury. Recently, we have designed a peptide, termed EmtinB, which is modeled after the ฮฒโ€domain of MTโ€II and mimics the biological effects of MTI/II in vitro. Here, we demonstrate the neuro