The purpose of the present study was to assess the role of dopamine D 1 and D 2 receptors in the discriminative stimulus properties of the atypical antipsychotic clozapine (CLZ). Two groups of rats were trained to discriminate either a moderate dose of clozapine (5.0 mg/kg) from vehicle or a high do
Nicotine does not interact with the discriminative stimulus effects of clozapine in rats
β Scribed by Heidi F. Villanueva; Shahwali Arezo; John A. Rosecrans
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 438 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0272-4391
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The present study was designed to investigate the eects of centrally administered morphine and opioid peptides on the discriminative stimulus properties of pentazocine in the rat. Rats were trained to discriminate 3 mg/kg (s.c.) of pentazocine from vehicle in a shock avoidance paradigm. A 3 mg/kg (s
The effect of unilateral intrapallidal cannabinoid receptor stimulation on rotational behavior in rats was explored. The potent cannabinoid agonist CP55,940 (5 Β΅g/0.5 Β΅l) induced ipsilateral turning when microinjected unilaterally into the globus pallidus. The D 2 dopamine agonist quinpirole reverse