Nickel nanoparticle-catalyzed facile and efficient one-pot synthesis of polyhydroquinoline derivatives via Hantzsch condensation under solvent-free conditions
β Scribed by Suryakant B. Sapkal; Kiran F. Shelke; Bapurao B. Shingate; Murlidhar S. Shingare
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- French
- Weight
- 264 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0040-4039
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## Abstract The synthesis is advantageous with regards to short reaction times, simple experimental and workβup procedures.
## Abstract magnified image Glycine, a novel heterogeneous organocatalyst, is found to be highly effective for the synthesis of polyhydroquinoline derivatives in a oneβpot multicomponent reaction __via__ Hantzsch condensation under controlled microwave (MW) irradiation. The combination of glycine
## Abstract Polyhydroquinolines have been synthesized in good to excellent yields (80β90%) and short reaction times (15β30 min) in the presence of aluminum phosphate [AlPO~4~] as heterogeneous catalyst at 90Β°C; the reaction workup is simple and the catalyst aluminum phosphate [AlPO~4~] can be easil
## Abstract magnified image An efficient and convenient method for the preparation of pyrimidine and quinazoline derivatives by the oneβpot reaction of aromatic aldehydes, cyclic ketones and guanidine carbonate, in the presence of sodium hydroxide under solventβfree condition was reported. This me