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NG-allyl- and NG-cyclopropyl-L-arginine: two novel inhibitors of macrophage nitric oxide synthase

✍ Scribed by Olken, Norman M.; Marletta, Michael A.


Book ID
121710908
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
1002 KB
Volume
35
Category
Article
ISSN
0022-2623

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Inhibition of Bovine Brain Nitric-Oxide
✍ J.G. Robertson; M.S. Bernatowicz; A.M. Dhalla; B.B. Muhoberac; J. Yanchunas; G.R πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 426 KB

Three derivatives of the mechanism-based inhibitor \(N^{\mathrm{G}}\)-allyl-L-arginine, designed to eliminate the effect of charge on the \(\alpha\)-functional groups, were synthesized and tested as inhibitors of purified bovine brain nitric oxide synthase. The inhibitory properties of \(N^{\mathrm{