c-FLIPS reduces activation of caspase an
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Jennifer Hinshaw-Makepeace; Gail Huston; Karen A. Fortner; Jennifer Q. Russell;
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Article
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2008
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John Wiley and Sons
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English
⚖ 317 KB
## Abstract Effective stimulation of NF‐κB in T cells following TCR ligation requires the activity of caspase‐8. The active caspase‐8 complex includes the paracaspase, MALT1, and Bcl‐10, which connect to the NF‐κB pathway. It has been less clear what regulates the level of caspase‐8 activity during