Although SRY was first identified 10 years ago, we still know remarkably little about its mode of action or downstream target genes. Recently, potential protein partners have been identified and there has been considerable activity to understand the roles of WT1, SF-1, DAX-1 and SOX9 in gonadogenesi
New Y chromosomes and early stages of sex chromosome differentiation: sex determination inMegaselia
โ Scribed by Walther Traut
- Book ID
- 107586165
- Publisher
- Indian Academy of Sciences
- Year
- 2010
- Tongue
- English
- Weight
- 152 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0022-1333
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In mammals, male sex determination, as well as spermatogenesis, is controlled by genes on the Y chromosome. Evolutionary comparisons may be used to detect and test candidate genes for these functions, under the hypothesis that the rapid evolution of the mammalian Y chromosome causes it to contain fe
## Abstract Sex determination in major vertebrate groups appears to be very variable, including systems of male heterogamety, female heterogamety and a variety of genetic and environmental sex determining systems. Yet comparative studies of sex chromosomes and sex determining genes now suggest that