New variant t(9;11;14)(p22;q23;q24) suggests a translocation of 9p to 11q as the critical genetic event
β Scribed by Ikuo Miura; Akihiko Yamaguchi; Hiroshi Takatsu; Akira B. Miura
- Book ID
- 119105764
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 194 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0165-4608
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A case of partial trisomy 9 is described in a mentally retarded and dysmorphic child, confirming that this chromosome unbalance results in a characteristic clinical entity. This trisomy arose through aberrant segregation of translocation chromosome during meiosis in the patient's mother, who is a ba
## Abstract Chronic myeloid leukemia (CML) is characterized by the presence of a t(9;22)(q34;q11.2), which leads to the wellβknown BCRβABL1 fusion protein. We describe a patient who was diagnosed clinically with a typical CML but on cytogenetic analysis was found to have a t(9;22)(p24;q11.2). Chrom