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New understanding of the molecular mechanism of receptor-mediated genomic actions of the vitamin D hormone

✍ Scribed by Haussler, M.R.; Jurutka, P.W.; Hsieh, J.-C.; Thompson, P.D.; Selznick, S.H.; Haussler, C.A.; Whitfield, G.K.

Book ID
122705185
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
581 KB
Volume
17
Category
Article
ISSN
8756-3282

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## Abstract The biologically active metabolite of vitamin D, 1,25‐dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) is a secosteroid whose genomic mechanism of action is similar to that of other steroid hormones and is mediated by stereospecific interaction of 1,25(OH)~2~D~3~ with the vitamin D receptor (VDR