New triazole antifungal agents derived from mercaptomethylisoxazoles
✍ Scribed by M. Moreno-Mañas; Y. Arredondo; R. Pleixats; M. Teixidó; M. M. Raga; C. Palacín; J. M. Castelló; J. A. Ortiz
- Book ID
- 112130477
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1992
- Tongue
- English
- Weight
- 296 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0022-152X
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The first generation antifungal agent triazoles, fluconazole and itraconazole, have revolutionised the treatment of serious fungal infections such as mucosal and invasive candidiasis and cryptococcal meningitis. However, the treatment of some fungal infections, particularly aspergillosis, is still f
## Abstract magnified image Novel C‐acylated triazoles were synthesized from ravuconazole __via__ bicyclic triazole lactone. The synthesis and antifungal activity of these C‐acylated derivatives are described.